Reply: Glycine as a key element of remote ischaemic conditioning cardioprotective signalling
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چکیده
منابع مشابه
Remote ischaemic conditioning: cardiac protection from afar
For patients with ischaemic heart disease, remote ischaemic conditioning may offer an innovative, non-invasive and virtually cost-free therapy for protecting the myocardium against the detrimental effects of acute ischaemia-reperfusion injury, preserving cardiac function and improving clinical outcomes. The intriguing phenomenon of remote ischaemic conditioning was first discovered over 20 year...
متن کاملRemote ischaemic pre-conditioning in cardiac surgery: benefit or not?
Hong et al. report the results of a randomized controlled trial in which 1280 patients who underwent elective cardiac surgery were randomized into a group who received remote ischaemic pre-conditioning (RIPC) combined with remote ischaemic postconditioning (RIPostC) or a control group. In the group who received remote pre-conditioning, four cycles of 5 min of ischaemia and 5 min of reperfusion ...
متن کاملEndogenous cardioprotection by ischaemic postconditioning and remote conditioning.
Persistent myocardial ischaemia causes cell death if not rescued by early reperfusion. Millions of years in nature's laboratory have evolved protective responses that 'condition' the heart (and other tissues) to adapt to stressors, and these responses are applicable to the relatively new societal stress of myocardial ischaemia and reperfusion injury. Conditioning can be applied before (precondi...
متن کاملRemote ischaemic conditioning in percutaneous coronary intervention: a meta-analysis of randomised trials
INTRODUCTION It remains uncertain whether remote ischaemic conditioning (RIC) using cycles of limb ischaemia-reperfusion as a conditioning stimulus benefits patients undergoing percutaneous coronary intervention (PCI). AIM We performed a meta-analysis toassessthe effect of RIC in PCI. MATERIAL AND METHODS The PubMed, EMBASE, Web of Science, and CENTRAL databases were searched for randomised...
متن کاملRepeat remote ischaemic pre-conditioning for improved cardiovascular function in humans: A systematic review
BACKGROUND Single exposure to remote ischaemic pre-conditioning (RIPC) has been shown to be effective in reducing major adverse events during cardiac surgery. We evaluated the efficacy of repeated exposure RIPC to elicit improvements in cardiovascular function. METHODS A systematic search was conducted up until May 1st, 2015, using the following databases: EMBASE, PubMed (Medline), Web of Sci...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2017
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvx034